In a study including rats, who had induced gastric ulcers, those treated with Aloe Vera juice showed less gastric acid output than the control & gastric ulcer groups. The rats weighed between 200-250g and were treated with 200 mg per kg twice daily for 8 days.
Translation to Horse Dose
200mg per 2.2lbs
90,909mg for 1,000lb horse
90.9g = 3.21oz
Suggested dose for Aloe Vera Juice for gastric acid inhibition would be 6.42 oz daily.
Source
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Rats weighing between 150g-200g were sorted into separate groups. Groups were treated Aloe Vera Gum Acacia powder administered at 200mg/ kg and Omeprazole administered at 20mg/ kg. Aloe Vera group showed anti-ulcer activity comparable to the omeprazole group.
Horse Dose Translation
Aloe Vera: 3.21oz Daily
Omeprazole: 9.1g Daily
100% of control group had gastric ulcerations. 40% of Aloe Vera group had ulcerations and 20% of omeprazole had ulcerations. "A. vera extract inhibits acid secretion ay be due to the presence of lectins in the plant (Blitz et al., 1963)." "Aloe buettneri extract increases gastric mucus production (Kossi et al., 2011)." "...protective properties of the mucus barrier depends not only on it's gel-like structure, but are also related to the amount of thickness of the layer covering the mucosal surface. Mucus protects the gastric mucosa against irritants..."
Source
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